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Current Academic GPA (through 1st Semester Junior year):  Academic: 4.6 (W) / 3.93 (UW)

AP Courses Completed:  AP Precalculus, AP European History, AP Spanish, AP Computer Science A / Java

AP Courses In Progress:  AP Biology, AP Chemistry, AP Calculus BC, AP English Language & Composition, AP US History

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RESEARCH & PUBLICATIONS

UCSD Bioengineering Internship – OPALS Program / Institute for Engineering in Medicine

Group Leader  |  Spring 2026 · Summer 2025 · Fall 2025

 

Computational dry-lab research on cortical neuron and astrocyte dynamics in traumatic brain injury models, using fluorescence image analysis (MATLAB, ImageJ/Fiji).

Leading development of a multi-class automated analysis platform: a two-stage U-Net segmentation and CNN classification pipeline that identifies and differentiates cortical neurons, astrocytes, and background; measures necrosis progression over time; and quantifies radius of cellular detachment as a novel spatial injury metric. Architecture designed for future extension to calcium wave propagation analysis and generalization across multiple cell types.

Completed Presentations

  • Oral Presentation — ICBEB International Conference on Biotechnology and Bioengineering, Nov 4–7, 2025, Matsue, Japan

    • “Investigating Mice Cortical Neuron Dynamics Following Laser-Induced Shockwave and Carbenoxolone Treatment”

  • Poster Presentation — BMES Annual Convention, San Diego, CA, October 2025 — High School Expo Division

    • “Disruption of Astrocyte Communication by Carbenoxolone During Shockwave Induced Stress” — Abstract Co-Author & Presenting Author

 

In Progress / Upcoming

  • First-Author Conference Proceedings & Oral Presentation – SPIE Optics and Photonics (San Diego, August 2026 — abstract accepted)

    • “Discovering the Role of Carbenoxolone in Preventing the Second Stage of Traumatic Brain Injury Using Laser-Induced Shockwave”

  • Two-stage U-Net segmentation and CNN classification pipeline (current) — targeting conference presentations and first-author journal publication

 

JPL (Jet Propulsion Laboratory) – Research Engagement

Dr. Art Chmielewski (JPL)  |  Spring, Sophomore Year

  • Conducted background research on the Emirati Mission to the Asteroid Belt and its key stakeholders in advance of a high-level meeting between JPL and the UAE team

  • Produced a briefing PowerPoint presentation delivered to Dr. Chmielewski’s JPL team as a preparatory resource for the meeting

INDEPENDENT RESEARCH

Regeneron Science Talent Search – Project in Development

For the Regeneron Science Talent Search, an independent machine learning project is in development to classify ADHD and OCD from brain imaging data (fMRI/structural MRI), without relying on genetic or self-report measures. Using publicly available datasets — including ADHD-200 and the OCD Brain Imaging Consortium — the project is fully separate from OPALS lab work, and brings together computational image analysis skills developed there with deep learning techniques from self-study coursework.

ACTIVITIES & EXTRACURRICULARS

Self-Study & Independent Learning

  • Mandarin Chinese – Non-Native Self-Study (June 2024 – Present)

    • Over 225 lessons completed on iTalki with professional tutors; HSK3 certified; targeting HSK4 by summer 2026

  • Machine Learning Specialization – Andrew Ng (Coursera) (Spring 2026)

    • 3-course series: Supervised Machine Learning · Advanced Learning Algorithms · Unsupervised Learning, Recommenders & Reinforcement Learning

  • Harvard CS50 / edX – Introduction to Programming with Python (Fall 2025) — Self-study

Programs & Conferences

  • La Cañada Flintridge Sister Cities / JPL Space Academy  (Fall 2025)

  • Johns Hopkins Global Health Leaders Conference  (Summer 2025, upcoming Summer 2026)

  • Caltech WiSTEM  (Summer 2025)

High School Clubs

  • Spanish Club — Treasurer (Freshman/Sophomore), Co-President (Junior)

  • Chinese Club  (Sophomore / Junior)

  • Girls Who Code  (Junior)

  • 1000 Cranes Club  (Freshman / Sophomore)

Other

  • Girl Scouts of America (2016 – Present)

  • Z Ultimate Martial Arts — American Kenpo Blue Belt Green Stripe

  • Recreational piano and vocal performance

AWARDS & RECOGNITION

  • Student of the Quarter – World Language  |  Q3, Freshman Year

  • Student of the Quarter – Science  |  Q4, Freshman Year

  • Girl Scouts Silver Award – Leer Con Amistades

    • Designed and led a bilingual reading curriculum for young children at a low-income social services facility

  • National Spanish Language Test – Silver Award

  • AP Scholar with Honors

  • California Scholarship Federation

LANGUAGES

  • Spanish — Fluent (completed AP Spanish as a Freshman)

  • Mandarin Chinese — Intermediate; HSK3 certified (see Self-Study for detail)

  • English — Native

 

TECHNICAL SKILLS

  • Programming: Python, Java

  • ML & Data Science: TensorFlow, Scikit-learn, NumPy, Matplotlib, XGBoost, Pandas, Jupyter Notebook

  • Deep Learning & Computer Vision: U-Net, CNN, OpenCV

  • Bioimage Analysis: ImageJ / Fiji, MATLAB (Onramp Certificate · Desktop Tools & Troubleshooting Scripts Certificate), MATLAB Plotting, Prism

  • Dev Tools: pytest

  • APIs & AI: Google APIs, Gemini AI

© 2026 Alexis Kukkonen

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